Well, you can lose the other drivers in theory, as you'll be using the 1/4" ones
Just my sig... a hiccup I must fix!
I had problems with a number of the tools on my Powerlock. The 1/4" socket driver was not among them. I think it gives the tool a GREAT capacity for inexpensive expansions. Instead of being stuck buying proprietary bits (cough:Leatherman:cough), you can go down to the local hardware store to get sockets. And an inexpensive 1/4" to hex socket gets you access to all hex bits, for pretty much infinite driver abilities on the cheap. I have, however, heard of some issues with folks losing the little metal clip on the socket driver. So, heads up, there.Otherwise, yeah. I'd ditch the can opener, scissors, saw... semi-serrated blade... most any other tools in favor of the socket driver.
If you are anything like me you will forget to take the little socket adapter with you.... I think mine is on my bedside table at the min