The thing to remember with macro is that depth of field diminishes dramatically.
Stop the lens down to F16 or F22 if it has AV program (aperture priority) use that.
Put the camera on a tripod/bean bag or whatever to ensure crisp sharp pictures through the long exposures. Keep the film speed relatively low (personally I wouldn't go above ISO 200). Use ambient light with reflectors (white card/tin foil) to throw light where it's needed.
I imagine your camera will have a macro setting. If so use that too.
As for focus..... If it's multi-point set them for the beads, or focus and reframe or use manual focus.
Because the rocks are low contrast compared to the sharp profile on the beads, the camera should lock on straight away - the rocks may well cause the AF system to hunt.
Try to keep the beads all on the same plane - even stopped down to F22 the actual depth of focus in close up macro is usually very shallow.
Have fun